If you enjoy New Orleans Cajun food, you will love this Roast Beef Po Boy. It is a great way to use your leftover roast beef.  This post includes instructions to building a fabulous Cajun Roast Beef Po Boy plus a delicious slow cooker roast beef.

Roast Beef Po Boy Cajun New Orleans Style

A Po Boy is a traditional Louisiana sandwich.  It consists of roast beef or fried seafood like shrimp, crab, oysters, or fish.  New Orleans French Bread is a must for Po Boys. It has a crispy crust and a soft fluffy center.

A New Orleans Roast Beef Po Boy starts cooking the roast beef low and slow in the oven.  Cajuns make a delicious gravy out of the dripping from the roast and add small pieces of the roast into the gravy.  They serve this Debris on a New Orleans Roast Beef Debris Po-Boy.

Cajun Roast Beef Po Boy

The bread they serve the Po Boy on is always French bread.  You usually get a six or twelve inch Po Boy. They slice the French bread lengthwise. Generously, add mayonnaise on the top and bottom part of the bread.  My husband likes to add a little horseradish on one side. Next, they layer cheese, Swiss cheese generally, on one side of the French Bread.  Next, cover the cheese with a generous portion of hot roast beef debris.

What do you serve with Po Boys?

 New Orleans Gumbo


Cajun Potato Salad Shrimp



Roast Beef Po Boy

Top Half Of The French Bread

On the other side of the Roast Beef Po Boy, they add shredded lettuce and fresh slices of tomato with salt, pepper, and Cajun Seasoning.  It is incredibly messy and typically requires a knife and fork instead of picking it up.  Messy or not, a New Orleans Roast Beef Po Boy is out of this world.  The bread absorbs a lot of the gravy, and it is genuinely yumminess.

    in Covington, Louisiana.  

For my homemade version of a Roast Beef Po Boy, I cook the roast beef on low for ten hours in a slow cooker.

    I put


This Slow Cooker Roast Beef was cooked on low for ten hours in a slow cooker. It reminds me of New Orleans Roast Beef Debris. #slow cooker #crockpot #roast beef
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5 from 1 vote

Slow Cooker Roast Beef

This Slow Cooker Roast Beef was cooked on low for ten hours in a slow cooker.  It reminds me of New Orleans Roast Beef Debris.
Prep Time20 mins
Cook Time8 hrs
Course: entree
Cuisine: American
Keyword: crock pot, crockpot, entree, roast, roast beef, slow cooker
Servings: 12
Calories: 381kcal



  • Cover the roast with the flour salt and garlic.
  • Heat the oil and brown all sides of the roast.
  • Add the roast to the slow cooker.
  • Top with chopped onion, beef broth, Worcestershire sauce, celery, garlic, Cajun seasoning, rosemary, thyme, marjoram, and oregano.
  • Cook on low for 8 to 10 hours or until it easily shreds with a fork.


Calories: 381kcal | Carbohydrates: 7g | Protein: 31g | Fat: 26g | Saturated Fat: 14g | Cholesterol: 104mg | Sodium: 682mg | Potassium: 621mg | Fiber: 1g | Sugar: 1g | Vitamin A: 195IU | Vitamin C: 2mg | Calcium: 46mg | Iron: 4mg

Second Step: Your Slow Cooker Roast

Next, I chop it up into small pieces and make a gravy using the incredibly tasty broth the roast cooked in.  New Orleans Gravy is thinner than the gravy I make.  It is a must to use the liquid from the roast to make the gravy.

Roast Beef Po Boy

Now that the roast is ready let’s make the Po Boy.

Third Step: Bread

Fourth Step: Mayonnaise

Fifth Step: Cheese & Roast Beef

Sixth Step: Make the Gravy


Seventh Step: Add the Gravy and Toppings

Do Not Skip The Gravy

After layering the Swiss cheese and adding the roast beef, I add the gravy to the chopped roast.  It is a little less messy this way, but I serve additional broth from the slow cooker.  This way, you can dip the sandwiches into it.  This Roast Beef Po Boy can still be messy, but it is so worth it.  It is finger, licking good.

Roast Beef Po Boy

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Slow Cooker Roast Beef Po Boys #New Orleans #Po Boys #roast beef #sandwiches
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4.41 from 5 votes

Roast Beef Po Boy - New Orleans

These Cajun Roast Beef Po Boys are fabulous and easy to make using slow cooker roast beef.
Prep Time15 mins
Cook Time5 hrs 30 mins
Course: Sandwich/Po Boy
Cuisine: Cajun
Keyword: po boy, roast, roast beef, roast beef po boy, sandwiches
Calories: 981kcal


  • 6 inch French Bread
  • 1/2 cup Roast Beef Debris - See my Slow Cooker Roast Beef Debris recipe on blog)
  • Mayonnaise
  • 2 Slices Swiss Cheese
  • 1/2 cup shredded lettuce
  • 2 slices fresh tomatoes
  • Salt Pepper & Cajun seasoning to taste
  • GRAVY:
  • 1/4 cup butter
  • 1/4 cup all-purpose flour
  • 3 cups beef broth from the slow cooker the roast cooked in.


  • Cut the French Bread in half lengthwise
  • Spread Mayonnaise on both sides of the bread.
  • On the bottom side, add two pieces of slice cheese.
  • Add 1/2 cup of chopped roast beef.
  • Top the roast beef with hot gravy.
  • On the top half of the French Bread, add 1/2 cup shredded lettuce.
  • Top the lettuce with two slices of fresh tomato.
  • Season as desired with salt, pepper and Cajun season.
  • Heat oil in a skillet.
  • Whisk in 1/4 cup of flour.
  • Stir and cook until light brown.
  • Slowly whisk in the beef broth the roast was cooking in.  It is a must to use the beef broth from the roast.  It is loaded in seasonings.


It is a must to use the beef broth from my slow cooker roast.  It is loaded in seasonings.


Calories: 981kcal | Carbohydrates: 38g | Protein: 52g | Fat: 71g | Saturated Fat: 53g | Cholesterol: 99mg | Sodium: 5502mg | Potassium: 1028mg | Fiber: 2g | Sugar: 3g | Vitamin A: 913IU | Vitamin C: 62mg | Calcium: 658mg | Iron: 6mg

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